Abstract
Background:Surgical site infection is a severe complication of peripheral vascular surgery with high morbidity and mortality rates.Objective:To evaluate the morbidity and mortality of infections of peripheral artery surgery sites caused by resistant microorganisms.Methods:This was a prospective study of a cohort of patients who underwent peripheral artery revascularization procedures and developed surgical site infections between March 2007 and March 2011.Results:Mean age was 63.7 years; males accounted for 64.3% of all cases. The overall prevalence of bacterial resistance to antimicrobials was 65.7%. The most common microorganism identified was Staphylococcus aureus (30%). Comparison of the demographic and surgical characteristics of both subsets (resistant versus non-resistant) detected a significant difference in length of preoperative hospital stay (9.3 days vs. 3.7 days). The subset of patients with infections by resistant microorganisms had higher rates of reoperation, lower numbers of limb amputations and lower mortality, but the differences compared to the subset without resistant infections were not significant. Long-term survival was similar.Conclusions:This study detected no statistically significant differences in morbidity or mortality between subsets with surgical wound infections caused by resistant and not-resistant microorganisms.
Highlights
Surgical site infection is a severe complication of peripheral vascular surgery
Seven hundred patients were treated at our department using peripheral artery surgery
Data from seventy patients who developed surgical site infection after peripheral artery surgery were analyzed during the study, stratified into two subsets: those infected by resistant bacteria and those infected by non-resistant bacteria
Summary
Surgical site infection is a severe complication of peripheral vascular surgery. Surgical site infection occurs in 0.9-22% of arterial vascular surgeries, and recent series have reported rates of around 3%.1,2 Deep infection with involvement of the wall of the operated artery or the implanted graft occurs in 1.213% of arterial surgeries.[2,3] França et al reported a 4.6% incidence of synthetic graft infection in peripheral vascular surgery.[2]. Surgical site infection occurs in 0.9-22% of arterial vascular surgeries, and recent series have reported rates of around 3%.1,2. Treatment is complex, involving reoperation, use of wide-spectrum antimicrobials and extended hospital stays, resulting in high mortality (10-76%) and morbidity rates (8-53%).[2,3,4,5]. Surgical site infection is a severe complication of peripheral vascular surgery with high morbidity and mortality rates. Objective: To evaluate the morbidity and mortality of infections of peripheral artery surgery sites caused by resistant microorganisms. The subset of patients with infections by resistant microorganisms had higher rates of reoperation, lower numbers of limb amputations and lower mortality, but the differences compared to the subset without resistant infections were not significant. Conclusions: This study detected no statistically significant differences in morbidity or mortality between subsets with surgical wound infections caused by resistant and not-resistant microorganisms.
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