Mood Episode Recovery Changes Gear in the Intrinsic Clock

Abstract

Bipolar disorder, also known as manic-depressive illness, which affects three out of 200 people is a long-term disease, presents remittent depressive, hypomanic, manic or mixed episodes of illness, and bears a serious risk of death from suicide (Grande et al., 2016). About half of the time patients with bipolar disorder have symptoms impairing their work, social activities or relationships with others. Treatment focuses on preventing the recurrence of episodes and can clearly improve the outcome.