Abstract
Eosinophilic cystitis (EC) is a rare inflammatory disorder. We herein report a case of EC in an asthmatic female patient who had a recent exacerbation with none known allergen. She was administered montelukast sodium orally for four weeks and received complete remission. This medication was successfully discontinued after a three-month follow up period. This case report about successful treatment of an adult EC patient using montelukast sodium may provide a new option for EC patients with allergic history.
Highlights
Eosinophilic cystitis (EC) is a rare inflammatory disorder first reported by Brown in 1960 who described the condition as eosinophilic granuloma of the bladder.[1]
Eosinophilic cystitis is a rare inflammatory condition characterized by transmural eosinophilic infiltration of the bladder wall
Peripheral eosinophilia is found in nearly 40% of EC patients, which could aid in the diagnosis
Summary
Eosinophilic cystitis (EC) is a rare inflammatory disorder first reported by Brown in 1960 who described the condition as eosinophilic granuloma of the bladder.[1]. The cause of EC remains unclear, etiological factors including parasitic infection and intravesical instillation of chemotherapeutic agents (Mitomycin or Candthiotepa) or BCG have been reported.[2,3,4] Eosinophilic tissue infiltration is a heterogeneous group of diseases involving the respiratory system, gastrointestinal tract and skin. It is hypothesized that EC could be one kind of the eosinophilic tissue infiltration diseases, and eosinophilic infiltration in related organs like the respiratory tract could. Montelukast sodium was administered for four weeks and discontinued successfully after a three-month follow up period. This case report about successful treatment of an adult EC patient prompts montelukast sodium as an alternative for the current treatment modalities of EC patients with an allergic history
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
