Abstract
The TRIMAGE project aims to develop a brain-dedicated PET/MR/EEG (Positron Emission Tomography/Magnetic Resonance/Electroencephalogram) system that is able to perform simultaneous PET, MR and EEG acquisitions. The PET component consists of a full ring with 18 sectors. Each sector includes three square detector modules based on dual sstaggered LYSO:Ce matrices read out by SiPMs. Using Monte Carlo simulations and following NEMA (National Electrical Manufacturers Association) guidelines, image quality procedures have been applied to evaluate the performance of the PET component of the system. The performance are reported in terms of spatial resolution, uniformity, recovery coefficient, spill over ratio, noise equivalent count rate (NECR) and scatter fraction. The results show that the TRIMAGE system is at the top of the current brain PET technologies.
Highlights
Over the past 40 years, Positron Emission Tomography (PET) brain imaging has allowed unique insights into brain function under normal conditions and in disease states [1]
We showed the results of the brain PET component developed for TRIMAGE
A direct comparison can be done with the CareMiBrain (7%), MINDview (7%) and Won et al scanner (6.9%), as they evaluated the sensitivity following the same standard used in this paper
Summary
Over the past 40 years, Positron Emission Tomography (PET) brain imaging has allowed unique insights into brain function under normal conditions and in disease states [1]. Damage to neuronal function and reduced energy metabolism occur. 18F-FDG is the most widely used radiopharmaceutical, it is not the ideal tracer for brain imaging, owing to its high physiological cortical uptake and lack of specificity. This has opened the way for the introduction of several novel radiotracers, each with their own inherent strengths and limitations [2,3] that can increase the potential of brain imaging. The present and future availability of the new radiotracers have raised a new interest in brain-dedicated PET systems, especially if combined with magnetic resonance (MR), having superior performance than whole body systems
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
