Abstract
Four undescribed monoterpenoid indole alkaloids, melodinines X1‒X4 (1‒4), together with fourteen known ones, have been isolated from the fruits of Melodinus henryi. Their structures with absolute configurations were elucidated by extensive spectroscopic methods and ECD calculations. Compound 1 shows a significant cytotoxicity to HL-60 cancer cell line with an IC50 value of 0.8 μM.
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