Abstract

Aim: Isolated coronary artery ectasia (ICAE) is a rare form of coronary artery disease and has almost same mortality and morbidity rate to atherosclerotic coronary artery disease. Monocyte to HDL-cholesterol ratio (MHR) has been entered the literature as a new inflammatory indicator in various cardiovascular disease. In this study we want to investigate relationship between inflammatory and oxidative markers that high sensitive C reactive protein (Hs-Crp), MHR and ICAE.
 Material and Methods: We retrospectively observed patients who underwent elective coronary angiography. Patients with ICAE and normal coronary arteries included in the study. MHR and Hs-Crp levels were observed just before the coronary angiography procedure.
 Results: A total of 98 patients (61, 62 % men) patients were included in this study and 28 (28.6%) of them had DM. 68 (69.3%) of patients had ICAE. MHR was significantly higher in patients with ICAE (0.0153 (0.007-0.130)ve 0.0111 (0.005-0.020), p< 0.001). Hs-Crp was also significantly higher in patients with ICAE (Yd-Crp: 6 (0.2-33)ve 1(0.2-14), p < 0.001). MHR was also significantly correlated with Hs-crp levels (r:0,338, p: 0.001). Additionally; DM, smoking, HT, MHR and Hs-crp were detected as independent risk factors of ICAE in logistic regression analysis. In receiver operating characteristic curve analysis, the area under the curve for predicting CAE was 0.744 (p

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