Monopolar versus bipolar transurethral resection of the prostate: a Meta analysis

Abstract

Objectives To systematic review the efficacy and safety of monopolar versus bipolar transurethral resection of the prostate using Meta analysis. Methods PubMed, Embase, the Cochrane Library, Chinese biomedical literature database, Chinese Scientific Journals full-text database, Chinese Journal full-text database, and major conference proceeding for randomized controlled trials comparing monopolar with bipolar transurethral resection of the prostate for patients with benign prostatic hyperplasia were searched . Meta anlysis was carry out according to Cochrane handbook. The data were analyzed using Review Manager 5.2 provied by Cochrane collaboration. Results 16 randomized controlled trials (a total of 1986 patients) were included. The Meta analysis showed that there was not significant difference between monopolar group and bipolar group in Qmax[MD=0.34, 95%CI(-0.15, 0.82)]and clot retention incidence rate [RD=0.00, 95%CI(-0.01, 0.02)]. While bipolar group provided lower transurethral resection syndrome rate [RD=0.01, 95%CI(0.00, 0.03)] and clot retention [RD=0.03, 95%CI(0.01, 0.05)]. Conclusions Current clinical evidence indicates that no clinically relevant differences in Qmax exists between the two techniques, bipolar technology is superior to monopolar technology in safety. Key words: Prostatic Hyperplasia; Transurethral Resection of Prostate; Meta-Analysis