Monooxygenase, Peroxidase and Peroxygenase Properties and Mechanisms of Cytochrome P450

Abstract

Foreword.- 1. Monooxygenase, Peroxidase and Peroxygenase Properties and Reaction Mechanisms of Cytochrome P450 Enzymes .- 2. Oxidizing Intermediates in P450 Catalysis: A Case for Multiple Oxidants.- 3. Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand Interactions.- 4. Acyl-Carbon Bond Cleaving Cytochrome P450 Enzymes: CYP17A1, CYP19A1 and CYP51A1.- 5. Regioselective Versatility of Monooxygenase Reactions Catalyzed by CYP2B6 and CYP3A4: Examples With Single Substrates.- 6. Cytochrome P450 Enzymes in the Bioactivation of Polyunsaturated Fatty Acids and their Role in Cardiovascular Disease.- 7. Monooxygenation of Small Hydrocarbons Catalyzed by Bacterial Cytochrome P450s.- 8. Use of Chemical Auxiliaries to Control P450 Enzymes for Predictable Oxidations at Unactivated C-H Bonds of Substrates,- 9. Cytochrome P450 Enzymes and Electrochemistry: Crosstalk with Electrodes as Redox Partners and Electron Sources.- 10. Mechanistic Basis of Electron Transfer to Cytochromes P450 by Natural Redox Partners and Artificial Donor Constructs .- 11. Biological Diversity of Cytochrome P450 Redox Partner Proteins .- 12. Cytochrome P450cin (CYP176A1).- 13. Fungal Unspecific Peroxygenases: Heme-Thiolate Proteins that Combine Peroxidase and Cytochrome P450 Properties.