Abstract
Sjögren’s Syndrome (SS) is a chronic autoimmune disease characterized by exocrinopathy, with xerophthalmia and xerostomia. Patients with SS may exhibit extra-glandular features such as neurologic symptoms. Peripheral neuropathy is the most common neurological complication of primary SS (pSS). We report a case of a 71-year-old female with pSS admitted to the Internal Medicine ward due to sensorimotor symptoms and petechiae. From the extensive study carried out, emphasis is given to elevation of inflammatory markers and to nerve conduction study compatible with mononeuritis of multiple nerves. The diagnosis of mononeuropathy multiplex (MM) secondary to pSS was made. She was started on corticosteroid therapy, which allowed complete regression of the petechiae as well as symptomatic and functional improvement. However, new sensorimotor deficits were noted a few days later. The decision was made to start cycles of cyclophosphamide in association with corticosteroid and physical therapies, leading to deficit improvement. Currently, the patient is in remission with low-dose corticosteroid therapy.
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