Abstract
A heterogeneous group of diseases lead to mononeuritis multiplex and multiple skin ulcers. A 45-year-old man presented with multiple painful subcutaneous nodules with ulcerations, distal predominant weakness of both upper and lower limbs, reduced sensations over ulnar distribution of the right hand and high-grade intermittent fever for 2 months. The patient was diagnosed to have cutaneous polyarteritis nodosa based on clinical and histopathological evidence after ruling out other conditions. The patient was treated with prednisolone 1 mg/kg, which was tapered over months and azathioprine was added. When reviewed after 6 months he was afebrile, skin lesions were healed, and the power was improving. Mononeuritis multiplex and multiple skin ulcers have various etiologies. A detailed workup is essential to rule out other systemic diseases before making a diagnosis of cutaneous polyarteritis nodosa which is a benign disorder with a favorable outcome.
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