Abstract

cRNAs for wild type and a functionless mutant of sarcoplasmic reticulum (SR) Ca(2+)-ATPase were co-injected into Xenopus oocytes in various molar ratios. SR Ca(2+)-ATPase activity of the microsomal fraction prepared from the injected oocytes increased linearly with increasing amounts of wild type cRNA. This result suggests that monomers are functional units of membrane-bound SR Ca(2+)-ATPase.

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