Abstract
We propose a monocationic chlorin photosensitizer for antimicrobial photodynamic therapy of superficial localized infections. The antimicrobial activity of this specie towards planktonic forms of nosocomial anti-biotic resistant pathogens, viz. Pseudomonas aeruginosa, Enterobacter cloacae и Acinetobacter baumannii was studied and compared with the activity of the well-established photosensitizer “Fotoran e6”. Our results do indicate that monocationic chlorin provides efficient photoinactivation of all the three microorganisms and can be considered as a new agent for antimicrobial photodynamic therapy.
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