Abstract

1. Monoamine oxidase (MAO) was determined fluorometrically in male goldfish tissues, and the effects of specific inhibitors determined. 2. MAO activity in kidney > intestine > pancreas > brain ∼ liver > testis. Apparent Michaelis constant ( K m ) was higher in the first three and lower in the last three tissues. 3. Specific MAO type A inhibitors (harmaline, clorgyline) were much more effective than a type B inhibitor (deprenyl) in reducing MAO activity. 4. Apparently goldfish tissues contain only a single type A-like MAO.

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