Abstract
Monkeypox is a viral zoonotic disease belongs to the family Poxviridae and Orthopoxvirus genus. Transmission of monkey pox is through direct contact with infected animal and blood. Human to human transmission occur through respiratory route but previously so many studies are conducted to prove that monkey pox viruse was not transmitted through the respiratory route both in animals and humans. But now monkey pox is able to survive in humans due to genetic changes and human to human transmission is possible. Because it can be used as bioweapon, So there is a great need of having an antiviral drug which is effective against monkey pox virus.ST 246 proved effective in vivo and in vitro in infected animals and trials done safely on non-infected humans but no data is available about the effectiveness of ST 246 on monkey pox or Orthopox infected human treated with ST 246.Int. J. Soc. Sc. Manage. Vol. 4, Issue-2: 77-79
Highlights
Monkeypox is a viral zoonotic disease belongs to the family Poxviridae and Monkeypox was first discovered in a research lab in 1958 when two outbreaks of pock like disease occur in the monkeys which were kept their for research purpose, it is called monkey pox
Virus is able to sustain in humans and spread can occur between humans due to genetic variation of the monkey poxvirus (Kugelman et al.,2014)
Monkeypox was not transmitted through respiratory route and not able to sustain in humans but it is possible due to genetic changes
Summary
Monkeypox is a viral zoonotic disease belongs to the family Poxviridae and Orthopoxvirus genus.Monkeypox was first discovered in a research lab in 1958 when two outbreaks of pock like disease occur in the monkeys which were kept their for research purpose, it is called monkey pox. To identify the need of having an antiviral drug (ST-246) against monkey pox for treating infected humans. ST-246 proved an effective antiviral drug for the treatment of monkey pox in vitro by stopping the production of orthopoxvirus, and prevents the further release of viruse.
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