Abstract

ObjectivesFrom May-September 2022, 203 cases of monkeypox (MPX) were reported in the Tel Aviv (TA) District, Israel. We aim to report the first ongoing local transmission of MPX in Israel. MethodsWe analyzed the epidemiologic and clinical features of all cases of MPX notified to the TA District. Each case was contacted to verify the source of infection and locate potential contacts. ResultsAll cases were men; 195 (96%) were among men having sex with men, and 171 (84%) resided in the city of TA. Median age was 35 years. One case occurred in a healthcare worker. All cases had a self-limiting disease. ConclusionA combined public health campaign with vaccination against MPX of high-risk individuals leads to a decrease in disease rates. Enhanced surveillance and prevention among susceptible populations are warranted.

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