Abstract
Advanced Metabolic Analysis In article number 2101220, Qian, Fan, Jia, and co-workers have developed a nanoparticle enhanced laser desorption/ionization mass spectrometry platform to record aqueous humor metabolic fingerprinting (AH-MF) of retinoblastoma (RB) with high performance. Early and advanced RB patients are differentiated by machine learning of AH-MF and identified biomarkers with area-under-the-curve over 0.9 and accuracy over 80%. This work will contribute to advanced metabolic analysis of eye diseases.
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