Monitoring of minerals level in dialysate during hemodialysis treatment of kidney patients using LIBS technique.

Abstract

Chronic kidney patients may have difficulties in blood filtration to eliminate the waste from the blood andto maintain the level of the minerals in the blood. Hemodialysis (HD) is an artificial way to remove the waste from the blood of a kidney patient and to maintain the proper mineral level in the blood. Reverse osmosis (RO) water having less total dissolved solids (TDS) < 50 ppm is used to prepare dialysis fluid/dialysate in dialysis with two chemicals (electrolytes and salts such as sodium bicarbonate). To check the purity of RO water from various RO machines used to prepare dialysate, which is vital for the safety of the patient, the laser-induced breakdown spectroscopy (LIBS) technique has been used. Also, the amount of replacement of electrolytes/minerals between the blood of the patient and dialysate after dialysis has been checked/determined for two different machines: hemodialysis machine (HDM) and on-line hemo-dia filtration machine (on-line HDF machine). It is observed that the proper amount of electrolytes (Na, Ca, and Mg) are maintained/normalized (depending upon patient's need), excess K is removed, and excess urea and creatinine is removed continuously from the blood of a patient during dialysis treatment which is essential for the betterhealth of a kidney patient. Our results show that the RO water used in on-line HDF machine is purer (i.e., ultrapure); therefore, the quality of life of a kidneypatient may be better if dialysis is performed with the on-line HDF machine. The experimental results also show that the filtration capacity of the dialyzer decreases after reusing it many times for dialysis treatment.