MONITORING OF BKV LOAD IN URINE ALLOWS IDENTIFICATION OF PATIENTS WITH THE HIGH RISK FOR BKV-ASSOCIATED NEPHROPATHY SEVERAL WEEKS PRIOR TO DEVELOPMENT OF VIREMIA: ANALYSIS OF 4128 URINE AND SERUM SAMPLES

Abstract

TO020 – Figure 1 Abstract TO020 – Figure 2 plot identified 30/55 centres within 2sd from the UK mean for % patients achieving PO4<1.8mmol/L but also outlying centres, 7 units outside the 99.9% CIs and 18 centres between the 95%-99.9% CIs. The Monte Carlo analysis (Figure 2) showed marked uncertainty surrounding unit ranking e.g. Bristol, actual rank 20th (CI 10th-32nd) due to a large % of units lying within a relatively narrow range i.e.a small change in % with PO4<1.8mmol/L can cause a large change in rank. Certainty of ranking is improved at both extremes where differences in % with PO4<1.8mmol/L are greater e.g. Reading, actual rank 4th (CI 1st-10th) and is also a function of centre size due to characteristics of the underlying distribution. Conclusions: These data highlight the limitations of simple rankings. Providing dialysis centres with the additional data shown in this study would aid in comparison of centre performance against audit measures for quality of care.TO020 – Figure 2 plot identified 30/55 centres within 2sd from the UK mean for % patients achieving PO4<1.8mmol/L but also outlying centres, 7 units outside the 99.9% CIs and 18 centres between the 95%-99.9% CIs. The Monte Carlo analysis (Figure 2) showed marked uncertainty surrounding unit ranking e.g. Bristol, actual rank 20th (CI 10th-32nd) due to a large % of units lying within a relatively narrow range i.e.a small change in % with PO4<1.8mmol/L can cause a large change in rank. Certainty of ranking is improved at both extremes where differences in % with PO4<1.8mmol/L are greater e.g. Reading, actual rank 4th (CI 1st-10th) and is also a function of centre size due to characteristics of the underlying distribution. Conclusions: These data highlight the limitations of simple rankings. Providing dialysis centres with the additional data shown in this study would aid in comparison of centre performance against audit measures for quality of care. TO021 TRENDS IN HEPATITIS C PREVALENCE (1997-2006) AND ASSOCIATIONS WITH FACILITY PRACTICE PATTERNS: THE DIALYSIS OUTCOMES AND PRACTICE PATTERNS