Abstract
The importance of sampling frequency in the course of monitoring of mutagenic pollution of small rivers is shown, the Kotorosl River (a tributary of the Volga River) being taken as an example. In working out a sampling program, due consideration should be given for seasonal variations of the river hydrological regime and input of pollutants. Incorrect choice of sampling frequency may lead to one of the principal reasons for improper assessment of toxicogenetic situation. A water sampling program has been proposed for the Kotorosl River studies based on monitoring.
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