Monitoring and analysis of perinatal defects in Lishui city in last decade

Abstract

Objective To analyze the dynamic changes of perinatal defects in Lishui city from 2005 to 2014. Methods According to hospital-based data, 87 294 fetuses and infants aged from 28 weeks of gestation to 7 days after birth were monitored for birth defects in Lishui city from 2005 to 2014. Results Among 87 294 perinatal infants, birth defects were found in 1 914 cases with a incidence of birth defects of 219.3/ten thousand, which was on the rise year by year except 2009. The incidence of birth defects was 235.1/ten thousand (737/31 352) in urban areas, which was significantly higher than that in rural areas (210.4/ten thousand, 1 177/55 942) (χ2=5.705, P 0.05). Among 1 914 cases of defects, 657 were detected prenatally and 1 257 case were detected within 7 days after birth. Congenital heart disease was the most common birth defect, followed by polydactyly, cleft lip, microtia and syndactyly. Birth defect accounted for 32.74% (278/849) of all perinatal deaths and the ratio was on the rise since 2010. Conclusion There is an upward trend in incidence of birth defects in Lishui city in the last decade; the incidence of birth defects in urban areas is significantly higher than that in rural areas; the incidence of congenital heart disease is high, and birth defects are the main cause of perinatal death. Key words: Congenital abnormalities; Perinatal period; Incidence; Cross-sectional studies