MON-LB098 Socioeconomic Status and Racial/Ethnic Factors Do Not Affect Thyroid Cancer Staging in an Urban Hospital with a Diverse Population Using the ThyroCARE Registry

Abstract

Background: Socioeconomic status (SES) and racial/ethnicity (R/E) may influence the stage, response to therapy and risk of death of thyroid cancer. We examined our comprehensive THYROid CAncer REgistry (ThyroCARE) at an urban tertiary care hospital with a diverse, urban population, many of whom are from minority and international backgrounds for the effect of SES and R/E on staging of thyroid cancer. METHODS: The ThyroCARE registry contains 1208 data points related to patient management. Data are captured via individual record review. Based on the patient’s zip code, the median household income is inferred from the 2016 US census data. RESULTS: ThyroCARE contains 1,212 patients (78.3% female; 21.7% male) enrolled between January 2000-present. Patients in ThyroCARE were 68.4% Caucasian, 10.3% Black, 13.4% Hispanic, 4.5% Asian, and 3% other, of which, 31% are foreign born. A difference in education was seen. More Caucasian patients received 2-4 years of college as well as graduate or professional education compared to patients from non-Caucasian R/E (31.4% vs. 12.0% and 19.8% and 8.2%, p<0.01). Caucasian patients have a higher median household income than African American, Hispanic, and Asian patients. ($79,545 vs. $57,056, p<0.001; $79,545 vs. $52,125, p<0.001; $79,545 vs $65,173.5, p<0.005, respectively). Caucasian patients have more classic papillary carcinoma than other R/E (75.8% vs. 70.4% p<0.01). Other R/E had more follicular variant PTC than Caucasians (23.3% vs. 18.5%, p<0.05). No significant differences in the initial ATA staging (2015) or AJCC staging (8th edition) among all racial groups were found. There was no significant correlation between income and the AJCC staging of the cancer at initial presentation (r=-0.003, p=0.895). Within each race, there was no significant correlation between income and the AJCC staging (Asian r=0.094, p=0.536; Black r=0.069, p=0.486; Hispanic r=0.035, p=0.694; and Caucasian r=-0.035, p=0.386). CONCLUSIONS: ThyroCARE is a large, comprehensive longitudinal thyroid cancer registry based in an urban, academic center whose patients are racially, ethnically, and socioeconomically diverse. Query of this registry did not demonstrate a difference in the ATA initial staging or AJCC 8th edition clinical staging based on SES or R/E factors. These results suggest that other factors in our medical center including access to high quality medical care contribute to the initial staging and response to therapy of thyroid cancer rather than SES and R/E. Unless otherwise noted, all abstracts presented at ENDO are embargoed until the date and time of presentation. For oral presentations, the abstracts are embargoed until the session begins. s presented at a news conference are embargoed until the date and time of the news conference. The Endocrine Society reserves the right to lift the embargo on specific abstracts that are selected for promotion prior to or during ENDO.