Abstract
The endothelial glycocalyx lines the lumen of blood vessels and has protective effects on the microvasculature. Damage to this layer can be detected as an increase of its shed constituents in blood, and an increase in the perfused boundary region (PBR) in sublingual vessels using the novel GlycoCheckTM device. In vitro studies have shown toxic effects of aldosterone and a high-salt environment on the glycocalyx that are attenuated by spironolactone. Spironolactone is known to have antiproteinuric and vasculoprotective effects in kidney transplant recipients (KTR).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
