Abstract

Positive salt and water balance with persistently elevated blood pressure (BP) leads to increased cardiovascular (CV) mortality in patients with End stage renal disease (ESRD) on chronic hemodialysis (HD). Apart from dietary sodium, the high dialysate sodium during dialysis also contributes to sodium gain. The adjustment of dialysate sodium has a potential to achieve euvolemia and control BP. We conducted a prospective crossover trial to investigate the effect of individualized dialysate sodium compared to standard uniform dialysate sodium on interdialytic weight gain (IDWG) and control of BP.

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