Mollaret cells detected in a patient with varicella-zoster virus meningitis

Abstract

Mollaret cells, which are observed in recurrent aseptic meningiis (Mollaret meningitis), have a unique bean-shaped nucleus with uclear clefts and are extremely fragile and difficult to detect for ore than 24 h after the appearance of symptoms [1]. The presnce of herpes simplex virus-2 (HSV-2) in the cerebrospinal fluid CSF), as detected by polymerase chain reaction (PCR), has recently een associated with Mollaret meningitis [2,3]. We present the rst report of a patient diagnosed with varicella-zoster virus (VZV) eningitis with Mollaret cells in CSF.