Molecularly Imprinted Polymer (MIPs) Nanomaterials Modified as Absorbing Cholesterol

Abstract

Nanomaterial Molecularly Imprinted Polymer (MIPs) from Methacrylic acid (MAA), Ethylene glycolmethacrylate (EGDMA), 2,2-Dimetoksi-2-Phenyliacetonephenon (DMPP) and cholesterol have been successfully synthesized by using the photopolymerization method. MIPs has been characterized by Scanning Electron Microscope (SEM) to see the physical shape and size of his fingers, while FTIR was used to analysis of the cholesterol extraction and re-extraction in MIPs. The absorption capacity of MIPs against cholesterol in solution was analyzed by the calorimetry method using Liebermann-Burchard reagent. MIPs absorption of cholesterol in the blood was analyzed by using Easy Touch GCU. The results of SEM analysis showed that MIPs were spherical with a diameter of 1,038µm to 2.702µm. While FTIR analysis shows that MIPs cholesterol can be extracted and re-extracted in MIPs. MIPs absorption against cholesterol in solution is 84.49% for 0.30 grams of MIPs and time of absorbance is 30 minutes. While the absorption of MIPs against cholesterol in the human blood is 41.19%, it shows that pores and active groups of MIPs are able to absorb and selectively to cholesterol molecules.