Molecularly Imprinted Polymer for Solid-Phase Extraction of Phenolic Acids from Salicornia herbacea L.

Abstract

This paper reports the application of a molecularly imprinted polymer (MIP) for the extraction and separation of phenolic acids from Salicornia herbacea L. (S. herbacea) using a solid phase extraction (SPE) system. The template of the MIP for phenolic acid extraction and separation was selected experimentally as one of seven templates. The obtained material with Benzoic acid (BA) as a template had the best extraction capacity of phenolic acids from S. herbacea. Water and methanol/HCl were selected as a washing solvent and elution solvent, respectively. The good linearity was obtained for the three targets, ranging from 10 to 500 μg mL−1 (R2 > 0.999), with relative standard deviations ≤ 5.0%. Overall, the proposed method using MIPs is expected to have a wide range of applications.