Abstract
BackgroundPeste des petits ruminanats (PPR) is an economically important viral disease affecting goats and sheep. Four genetically distinct lineages of peste des petits ruminants virus (PPRV) have been identified. In Gabon, the virus has not so far been detected.FindingsEpidemiological investigations of Aboumi PPR outbreak revealed a high case fatality rate in sheep (98.9%). We detected and characterized peste des petits ruminants virus (PPRV), in October 2011, during the suspected outbreak in sheep and goats in Aboumi village located in the south-eastern. PPRV RNA was detected in 10 of 14 samples from three sick animals. Phylogenetic analysis revealed that the PPRV strain belonged to lineage IV and was closely related to strain circulating in neighboring Cameroon.ConclusionsThis is the first molecular detection and typing of the PPRV strain associated with fatal PPR infection in these small ruminants and concrete evidence that PPRV is present and circulating in Gabon.
Highlights
Peste des petits ruminants (PPR) is a highly contagious disease caused by Peste des petits ruminanats (PPR) virus (PPRV, family Paramyxoviridae, genus Morbillivirus)
This is the first molecular detection and typing of the peste des petits ruminants virus (PPRV) strain associated with fatal PPR infection in these small ruminants and concrete evidence that PPRV is present and circulating in Gabon
In this report we describe an outbreak of PPR in goats and sheep in Gabon and provide the first molecular characterization of the PPRV lineage associated with fatal PPR infection in these small ruminants
Summary
Peste des petits ruminants (PPR) is a highly contagious disease caused by PPR virus (PPRV, family Paramyxoviridae, genus Morbillivirus). PPR primarily affects sheep and goats, with case fatality rates reaching 90% in naive populations [2]. PPR is one of the main transboundary animal diseases and represents a major threat to small ruminants [3]. It is considered the most economically important viral disease of sheep and goats in enzootic regions, where it has a major impact on the food supply. Peste des petits ruminanats (PPR) is an economically important viral disease affecting goats and sheep. Four genetically distinct lineages of peste des petits ruminants virus (PPRV) have been identified. In Gabon, the virus has not so far been detected
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