Abstract
The size of the vanilloid receptor was examined by high-energy radiation inactivation analysis of the binding of [ 3H] resiniferatoxin to pig dorsal root ganglion membranes; it was found to be 270 ± 25 kDa. This value most likely represents the size of a receptor complex rather than of an individual subunit. Other ligand-gated cation channel complexes have reported molecular weights in this range, e.g. 300 kDa for the acetylcholine receptor.
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