Abstract

Mol Syst Biol. 1: 2005.0005 While Molecular Systems Biology may be a new journal, there has been considerable debate as to whether systems biology itself represents a new approach to biology or whether it is really just a new and catchy name for what some biologists have been doing all along. The answer to this question of course depends on how one defines systems biology. Terms that have already been used to describe systems biology include comprehensive biology, postgenomic biology, quantitative biology, mathematical modeling of biological processes, multidisciplinary biology, molecular physiology, the convergence of biology and computer science, and more. These terms do not actually describe systems biology as anything new. However, those who, like the author of this feature, believe that systems biology in fact does represent a new approach to the life sciences have therefore been challenged to produce a definition that reflects this view. Perhaps surprisingly, a concise definition of systems biology that most of us can agree upon has yet to emerge. In order to come up with such a concise definition, we should first consider what systems biology aims to …

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