Abstract

Abstract The invention and development of new research concepts, novel methodologies, and novel bioanalytical techniques are essential in advancing the animal sciences, which include feed and nutrition science. This article introduces a novel approach that shows the potential of advanced synchrotron-based bioanalytical technology for studying the effects of molecular structural changes in feeds induced by various treatments (e.g., genetic modification, gene silencing, heat-related feed processing, biofuel processing) in relation to nutrient digestion and absorption in animals. Advanced techniques based on synchrotron radiation (e.g., synchrotron radiation infrared microspectroscopy (SR-IMS) and synchrotron radiation X-ray techniques) have been developed as a fast, noninvasive, bioanalytical technology that, unlike traditional wet chemistry methods, does not damage or destroy the inherent molecular structure of the feed. The cutting-edge and advanced research tool of synchrotron light (which is a million times brighter than sunlight) can be used to explore the inherent structure of biological tissue at cellular and molecular levels at ultra-high spatial resolutions. In conclusion, the use of recently developed bioanalytical techniques based on synchrotron radiation along with common research techniques is leading to dramatic advances in animal feed and nutritional research.

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