Abstract
Background: Cancer research is significantly improved by comprehensive DNA sequencing and profiling. Genes involved in diagnostic, prognostic, or therapeutic consequences have been extensively studied using high-throughput sequencing. Thus, precision medicine based on cancer genotype has been developed, leading to improved survival. The fifth edition of the World Health Organization Classification of Tumors specified a diagnostic molecular pathology section under each disease category. Methods: We highlight the molecular aspects in research and diagnostics of diverse gynecological malignancies using database resources in addition to data mining software tools. Results: This review article presents insight into various gynecological cancers and their different characteristics, offering better profiling for switching to better therapeutic options. Conclusions: Genomic profiling is evolving as a clinically feasible tool for personalizing treatment. It can provide insight regarding treatment plans for common gynecological cancers.
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