Abstract
We have reported a dumbbell-shaped structure of dystrophin molecule (Murayama et al., 1990; Sato et al., 1992). However its small population has raised a possibility that the dumbbell structure was due to a contaminant protein, such as type VI collagen of aorta origin. In the present study, type VI collagen was purified from bacterial collagenase-treated aorta of the rabbit. Its rotary shadowed images were very similar to those present in the dystrophin preparations. However, the antiserum to type VI collagen raised in a mouse did not react with dystrophin samples. A tentative explanation for the small population of the dumbbell structure is described.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
