Abstract

Lipid membranes are self-organizing structures that define intercellular and intracellular interfaces in biological systems. Grazing incidence x-ray diffraction (GIXD), provides a sensitive probe of the local, molecular structure and packing of lipid molecules within single membranes. For example, diffraction clearly establishes that dipalmitoyl-phosphatidylcholine (DPPC) membrane leaflets are always coupled across the bilayer, and that even when leaflets are deposited independently the membrane rapidly self-organizes so that opposing lipid tails scatter as one entity.

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