Molecular Resonance vs. Coblation Tonsillectomy in Children

Abstract

Objective To compare molecular resonance (MRT) with coblation (CAT) devices for pediatric tonsillectomy. Methods Prospective, 2-group, randomized trial in a tertiary care pediatric institution. 89 children for whom tonsillectomy was indicated were randomly assigned to receive MRT (n=45) or CAT (n=44). Main outcome measures included intraoperative time, blood loss, postoperative pain, and weight loss. Histopathologic examination was performed on all excised tonsils. Patients, parents, and pathologist were blinded to surgical modality. Results Histopathologic evaluation revealed significantly reduced thermal injury with MRT than with CAT (43 microns vs. 126 respectively, p<0.001), and was statistically associated with reduced muscular, blood vessels, and nerve fibers damage. No intraoperative blood loss was observed in patients following MRT. Statistically significant reduced pain scores were related to the MRT (p<0.002). In addition, the MRT method showed a quick return to normal diet with even weight gain during the 10-day postoperative period. One child in the CAT group experienced delayed bleeding and required read-mission. Conclusions Molecular resonance for pediatric tonsillectomy resulted in significantly reduced histopathologic thermal injury, and lower pain scores as compared to coblation. Further studies are advised to support these data.