Abstract

Molecular Psychiatry, August 2020: new impact factor, and highlights of recent advances in psychiatry, including an overview of the brain\u2019s response to stress during infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Highlights

  • This year we published four special issues, one on schizophrenia [1–19], one on stress and behavior [20–38], and two on depression, in June [39–55] and July [56–76]

  • Dempster et al present a 7-T magnetic resonance spectroscopic study of glutathione and glutamate showing early treatment response in first-episode psychosis [82]; Niculescu et al present intriguing work on blood biomarkers for memory that can be targeted toward early detection of risk for Alzheimer’s disease (AD), pharmacogenomics, and repurposed drugs [83], and Polimanti et al leverage genome-wide data to investigate differences between opioid use versus opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium [84]

  • In other original research articles, we present key new advances across multiple fields

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Summary

Introduction

This year we published four special issues, one on schizophrenia [1–19], one on stress and behavior [20–38], and two on depression, in June [39–55] and July [56–76]. [79] These exciting Perspectives are followed by three important Reviews: by Prieto et al on post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction; by Rogdaki et al, a meta-analysis of the magnitude and heterogeneity of brain structural abnormalities in 22q11.2 deletion syndrome [80], and by Smigielski et al, a systematic review of empirical human findings on the epigenetic mechanisms in schizophrenia and other psychotic disorders [81].

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