Abstract
Glucose-6-phosphate dehydrogenase (G6PD) is the first key enzyme in the pentose phosphate pathway (PPP). Its catalysate—NADPH plays an important role not only in a series of biosynthesis, but also in keeping the balance between oxidizing and reductive substances in the body. G6PD deficiency is one of the most common inherited enzymopathy, and its distribution is higher in the south than the north China. This article summarizes the advances in studies on the molecular pathogenesis of G6PD deficiency, and the correlation between G6PD deficiency and other diseases including malaria, tumor and thalassemia. Key words: G6PD; G6PD deficiency; Malaria; Tumor; Thalassemia
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
