Molecular Mechanisms of Synaptogenesis

Abstract

Synaptogenesis: When Long-Distance Relations Become Intimate.- Synaptogenesis: When Long-Distance Relations Become Intimate.- Experimental Models of Synaptogenesis.- The Formation of the Vertebrate Neuromuscular Junction: Roles for the Extracellular Matrix in Synaptogenesis.- Synapse Formation between Identified Molluscan Neurons: A Model System Approach.- Development of the Drosophila and C. Elegans Neuromuscular Junctions.- Mechanisms That Regulate Neuronal Protein Clustering at the Synapse.- Roles of Cell Adhesion and Secreted Molecules in Synaptic Differentiation.- Cadherin-Mediated Adhesion and Signaling During Vertebrate Central Synapse Formation.- Synaptic Functions of the Neural Cell Adhesion Molecule, NCAM.- Role of Neuroligin Binding to Neurexins in Synaptic Organization.- SynCAM in Formation and Function of Synaptic Specializations.- Protocadherins and Synapse Development.- Ephrins and Eph Receptors in Spinogenesis and Synaptic Plasticity.- Extracellular Matrix Molecules and Formation of CNS Synapses.- Role of Neurotrophins in the Formation and Maintenance of Synapses.- Transport of Synaptic Proteins.- Motor-Cargo Interactions Involved in Transport of Synaptic Proteins.- Postsynaptic Transport Packets.- Lateral Diffusion of Excitatory Neurotransmitter Receptors During Synaptogenesis.- Synaptic Cytoskeleton and Morphogenic Signaling.- Assembly of Presynaptic Active Zones.- Assembly of Postsynaptic Protein Complexes in Glutamatergic Synapses.- Regulation of Dendritic Spine Morphology and Synaptic Function By Scaffolding Proteins.- Composition and Assembly of Gabaergic Postsynaptic Specializations.- Role of Synaptogenesis in Morphologic Stabilization of Developing Dendrites.- Protein Kinases and Synaptogenesis.- Signaling from Synapse to Nucleus and Back.- Synaptic Plasticity in Learning and Memory.- Structural Synaptic Correlates of Learning and Memory.- Intracellular Trafficking of AMPA-Type Glutamate Receptors.- Learning-Induced Changes in Sensory Synaptic Transmission.- Synaptogenesis and Brain Disorders.- Relevance of Presynaptic Proteins to Neuropsychiatric Disorders.- Synaptic Abnormalities and Candidate Genes in Autism.- Synaptic Pathology in Depression.- Synaptic Pathology in Dementia.- A Fragile Synapse: Changes at the Synapse in Fragile X Syndrome.- Synaptic Abnormalities Associated with Huntington's Disease.- Interference Peptides: A Novel Therapeutic Approach Targeting Synaptic Plasticity in Drug Addiction.