Abstract
In recent years, Knowledge about the biochemical nature of proteins involved in the synaptic exocytosis has rapidly increased, and SNARE-hypothesis, which assumes necessity of ATP hydrolysis by NSF protein before membrane fusion, has been proposed to explain sequential processes of exocytosis. However, some recent experimental data do not support the SNARE-hypothesis. New model (the zipper model) does not assume ATP hydrolysis before membrane fusion, rather it assume membrane fusion elicited by protein-protein interaction among syntaxin, SNAP-25 and VAMP. However, there remain many problems to be solved.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
