Abstract

Semiflexible polymers are of great biological importance in determining the mechanical properties of cells. We have used optical tweezers to trap pairs of micron-sized silica spheres in solutions of semiflexible polymers, and laser interferometry to detect their thermal motions with high bandwidth. Frequency-dependent complex shear moduli were extracted from the auto- and cross-correlated bead motions, with the response functions being derived from position-fluctuation data using dispersion relations from linear response theory.

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