Abstract

AbstractA high‐performance size exclusion chromatographic (HPSEC) method for molecular mass distribution (MMD) was developed for polycations. Results obtained from HPSEC using UV and RI detectors were compared with the viscosity measurements. Pullulan standards were used for Mw calibration. It is concluded that HPSEC with a UV detector offers a sensitive and simple method that has the required accuracy. Degradation studies following this method indicate that dextrans are stable at a temperature of 55 °C and at different pH solutions for up to 7 days. Copyright © 2003 John Wiley & Sons, Ltd.

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