Abstract
Omega-3 polyunsaturated fatty acids are believed to reduce the risk of death in patients with cardiovascular disease, and to alleviate the symptoms of a myriad of other inflammatory disorders, including non-alcoholic fatty liver disease. Although numerous attempts have been made to postulate explanations for the beneficial health effects of omega-3 fatty acids, the molecular mechanisms of action of these bioactive molecules remain unclear. In this study, we employed coarse-grained molecular dynamics computer simulations to examine changes to the biophysical properties of model cell membranes in response to varying physiological compositions of supplementation by omega-3 fatty acids.
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