Molecular insights into the jasmonate signaling and associated defense responses against wilt caused by Fusarium oxysporum

Abstract

Biotic and abiotic stress factors drastically limit plant growth and development as well as alter the physiological, biochemical and cellular processes. This negatively impacts plant productivity, ultimately leading to agricultural and economical loss. Plant defense mechanisms elicited in response to these stressors are crucially regulated by the intricate crosstalk between defense hormones such as jasmonic acid (JA), salicylic acid and ethylene. These hormones orchestrate adaptive responses by modulating the gene regulatory networks leading to sequential changes in the root architecture, cell wall composition, secondary metabolite production and expression of defense-related genes. Fusarium wilt is a widespread vascular disease in plants caused by the soil-borne ascomycete Fusarium oxysporum and is known to attack several economically important plant cultivars. JA along with its conjugated forms methyl jasmonate and jasmonic acid isoleucine critically tunes plant defense mechanisms by regulating the expression of JA-associated genes imparting resistance phenotype. However, it should be noted that some members of F. oxysporum utilize the JA signaling pathway for disease development leading to susceptibility in plants. Therefore, JA signaling pathway becomes one of the important targets amenable for modulation to develop resistance response against Fusarium wilt in plants. In this review, we have emphasized on the physiological and molecular aspects of JA and its significant role in mounting an early defense response against Fusarium wilt disease. Further, utilization of the inherent JA signaling pathway and/or exogenous application of JA in generating Fusarium wilt resistant plants is discussed.