Molecular identification, clinical assessment, characterization of SARS-CoV-2 RT-PCR results: Insights into twenty-one months of COVID-19 pandemic in a single center in Bangladesh

Abstract

Introduction: The pervasiveness of SARS-CoV-2 infection over millions of people renders a variety of symptoms among group of people and ages. This study aimed to appraise the clinical assessment, characterization, and comparative study on suspected SARS-CoV-2 infected patients and further illuminate its transmission dynamics. Methods: It includes all the suspected SARS-CoV-2 infected cases from July 2020 to March 2022 in this retrospective single center study. All the cases confirmed by the golden method of detection (real-time RT-PCR) and analyzed for clinical and demographic features and laboratory data. Result: Out of 35,630 cases, 11.4% cases confirmed with SARS-CoV-2 infection. With 91.4% new and 8.6% follow-up suspected cases in total, SARS-CoV-2 infection confirmed with 85.5% new cases and 14.5% from follow-up cases. 86.1% male suspected cases found where SARS-CoV-2 infection confirmed for 73.8% with this gender group. 56.7% SARS-CoV-2 infection confirmed for age range 20-39 and this age group counts 59.3% from the total suspected cases. Most confirmed cases (28.3%) counted from Uttara, Dhaka and this area covers 34.9% suspected cases from the total. Conclusion: This study exhibited that, SARS-CoV-2 is more prone to male individual, individuals aged between 20-39 and occurs re infection hardly but not limited to. Symptoms observed for almost half of the confirmed cases.