Abstract
After multiple discrete introductions of influenza A(H1N1)pdm09 virus into Sri Lanka, the virus was transmitted among humans, then swine. The spread of virus between geographically distant swine farms is consistent with virus dispersal associated with a vehicle used for swine transportation, although this remains unproven.
Highlights
After multiple discrete introductions of influenza A(H1N1)pdm09 virus into Sri Lanka, the virus was transmitted among humans, swine
The Study To understand the molecular epidemiology and spatial and temporal dynamics of spillover events, we compared our data with full-genome sequences of H1N1pdm available in public databases as of August 28, 2013
This study demonstrates natural independent spillover events of H1N1pdm influenza viruses from humans to swine
Summary
After multiple discrete introductions of influenza A(H1N1)pdm09 virus into Sri Lanka, the virus was transmitted among humans, swine. Reassorted swine or human viruses containing H1N1pdm virus genes were excluded from this analysis. Our final dataset included the full genomes of 35 human and 26 swine samples from Sri Lanka and a global sample of 1,057 human and 82 swine virus sequences.
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