Abstract

The fracture resistance of biomineralized tissues such as bone, dentin, and abalone isgreatly enhanced through the nanoscale interactions of stiff inorganic mineral componentswith soft organic adhesive components. A proper understanding of the interactions thatoccur within the organic component, and between the organic and inorganic components, istherefore critical for a complete understanding of the mechanics of these tissues. In thispaper, we use atomic force microscope (AFM) force spectroscopy and dynamicforce spectroscopy to explore the effect of ionic interactions within a nanoscalesystem consisting of networks of dentin matrix protein 1 (DMP1) (a componentof both bone and dentin organic matrix), a mica surface and an AFM tip. Wefind that DMP1 is capable of dissipating large amounts of energy through anion-mediated mechanism, and that the effectiveness increases with increasing ion valence.

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