Abstract
Affinity of thirteen 5-phenyl-5,6-dihydrotetrazolo[1,5-c]quinazolines and reference Tedizolid is calculated to penicillin-binding protein 2X (PBP 2X) (PDB ID: 2ZC4). The lead-compounds are proposed based on presented results, previous affinity towards ribosomal 50S protein L2P (2QEX), and their ADME profile. Besides, substance 12 has already shown good preliminary antifungal results towards C. albicans.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
