Molecular diagnosis in personalized therapy for cancer

Abstract

The current strategies of anti-cancer therapy are mainly based on the evidence-based medicine, which is much better than be based on the doctor's experience. But we still need to make attempts to find the right drugs and doses for each patient. The patients with the same disease may receive different response to the same treatment because of their inherited and somatic genetic variability. This results in greatly different therapeutic outcome. The determination of anti-cancer drugs and the doses based on the individual genotype will open up a new era of personalized therapy. Key words: Molecular diagnosis; Cancer; , Personalized; Chemotherapy