Abstract

Background During the past years an E coli clonal lineage ST131 has emerged explosively, causing predominantly communityonset antimicrobial resistant infections. E coli ST131 has been shown to harbor a number of virulence and resistance genes and is now recognized for its ability to cause potentially severe infections in many parts of the developing world, implying public health measures in attempt to control infection.

Highlights

  • During the past years an E coli clonal lineage ST131 has emerged explosively, causing predominantly communityonset antimicrobial resistant infections

  • By pabB PCR, we identified 22 (26%) E coli isolates belonging to the O25b-ST131 clonal lineage

  • Among patients with blood stream infections (BSI) caused by resistant E coli, the in-hospital mortality was similar in patients infected with strains carrying the ST131 clonal lineage (3; 14%) versus non ST131 (10; 17%) (p=0.921)

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Summary

Open Access

Molecular determinants of resistance in Escherichia coli-ST131 isolated blood stream infections. Adriana Hristea1,2*, Raluca Jipa, Ioana D Olaru, Cristina Popescu, Victoria Aramă, Ruxandra Moroti, Oana Streinu-Cercel. From The 9th Edition of the Scientific Days of the National Institute for Infectious Diseases Prof Dr Matei Bals Bucharest, Romania.

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