Abstract
The present study was aimed at detecting natural cases of canine monocytic ehrlichiosis (CME) by molecular and cytological methods and assessment of clinico-patho-biochemical parameters among the affected population. Nested polymerase chain reaction was found to be highly sensitive (47.7 %) in detecting the acute cases, followed by buffy coat (29.5 %) and blood smear examination (22.7 %). CME incidence rate was found to be 8.4 %. Hemogram revealed significant (P 0.05) reduction, whereas blood level of zinc showed significant (P < 0.05) reduction as compared to healthy controls. These findings revealed that changes in erythrocytic oxidant–antioxidant profile and blood mineral concentration in canine monocytic ehrlichiosis are largely non-significant and inconsistent. Hence, further study is required to elucidate their role in pathogenesis of canine monocytic ehrlichiosis.
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