Abstract

The organization within the cat genome of cellular genetic sequences homologous to the viral oncogene v- fms of the McDonough strain of feline sarcoma virus (SM-FeSV) was determined. Four cosmid clones containing overlapping v- fms homologous cellular DNA inserts representing a contiguous region of cellular DNA of approximately 80 kbp in length have been isolated from a feline cosmid gene library. Within this region of the cat genome, the c- fms genetic sequences are dispersed over a region of around 30 kbp and are interspersed with at least three intervening sequences.

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